To successfully treat endodontic infections, the clinician needs to accurately assess etiology, diagnosis and prognosis. One of the challenges the endodontist will face is the “perio-endo” lesion. In order to accurately access prognosis, the clinician needs to determine if the peri-radicular infection is related to periodontitis, endodontics, or both. The most important tool in assessing this is the probing depth and pattern related to the lesion. With an accurate assessment, treatment of these lesions can return teeth to normal function. The below x-rays are from initial, treatment, 4 month recall, and 1 year recall.